Abstract: The Cu-based pre-alloy powders were prepared by coprecipitation method in different ratios of Cu and Fe by mass (45:35, 50:30, 55:25), the Cu-based bonded diamond segments were fabricated by hot pressing method, and the Cu-based bonded diamond saw blades were manufactured by laser-welded method. The effects of Cu and Fe contents by mass on the properties of diamond saw blades prepared by Cu-based pre-alloyed powders were investigated. The fracture morphologies of saw blade surfaces were characterized by scanning electron microscope, and the hardness and abrasion loss of diamond saw blades were tested. The results show that, when the ratio of Cu and Fe by mass is 50:30, the combination between Cu-based bond and diamond is the optimal, the saw blades show the best performance as the maximum hardness of HRB 118 and the minimum abrasion loss of 1.16 g.