Abstract: Mo-Re-La alloys were prepared by solid-liquid doping method through adding La₂O₃ nanoparticles into Mo-Re alloys.Microstructures and mechanical properties of Mo-Re-La alloys, Mo-Re alloys, pure Mo were investigated.The results show that, the fine grain size strengthening of Mo-Re alloys is obvious by adding Re element into pure Mo in low mass fraction of 3.5%, and the Mo-Re-La alloys are further refined and strengthened by doping La₂O₃ nanoparticles into Mo-Re alloys.