Abstract: Molybdenum rhenium alloy is a solid solution strengthening alloy with high melting point and low expansion coefficient, and the addition of rare earth oxides can refine the grains and play a role in dispersion strengthening. In this paper, the microstructure and room temperature tensile fracture morphology of molybdenum rhenium alloy (Mo-14 % Re) and molybdenum rhenium lanthanum alloy sheet with 0.8 % (mass fraction) La2O3 were observed at different annealing temperatures, and the Vickers hardness and room temperature tensile properties were compared. The results show that with the increase of annealing temperature, the recrystallization temperature of molybdenum rhenium lanthanum alloy increases from 1200 °C to about 1400 °C compared with that of molybdenum rhenium alloy. The hardness and strength of molybdenum rhenium alloy and molybdenum rhenium lanthanum alloy gradually decrease, while the elongation of molybdenum rhenium lanthanum alloy gradually increases, up to 27.5 %.