Abstract: The La₂O₃ and ZrO₂ were doped in the molybdenum‒rhenium alloys, the effects of oxide doping on the relative density of the sintered billets and the mechanical properties of the final rolled plates at room temperature were studied in this paper. The results show that, the doped oxide can significantly reduce the particle size of the alloy powders. The grain size of molybdenum‒rhenium alloys doped with ZrO₂ is the smallest, but the relative density of the sintered billets is reduced due to the crystalline phase transformation. The rolling deformation can improve the hardness and strength of the alloy plates, the molybdenum‒rhenium alloys doped with La₂O₃ can obtain the higher strength with the plasticity almost unchanged, while the molybdenum‒rhenium alloys doped with ZrO₂ show the increase of strength but the decrease of plasticity. The tensile strength and yield strength of the molybdenum‒rhenium alloys doped with ZrO₂ are the highest, which are 1034 MPa and 888.2 MPa, respectively.