Abstract: To understand application trend of hot isostatic pressing powder metallurgy of titanium alloy, document retrieval, data extraction and quantitative analysis of patent literature in hot isostatic pressing powder metallurgy of titanium alloy was carried out. From the trends of application and technological in major countries, patent of hot isostatic pressing powder metallurgy of titanium alloy technology was revealed. The overall application trend of these global patent was shown as well. The results show that China has paid more attention to the application, University of Science and Technology Beijing, Central South University, Institute of Metal Research, Chinese Academy of Sciences, Beijing University of Aeronautics and Astronautics and Harbin Institute of Technology are the major research institution.