Abstract: In this study, the Mo2FeB2 based cermet coating was prepared on 06Cr13Ni4Mo steel by hot isostatic pressing(HIP) process, and the effects of HIP temperatures on the microstructures and mechanical properties of the Mo2FeB2 based cermet was studied. The results show that the coating mainly composed of hard phase(Mo2FeB2), bonded phase(Fe) and transition phase (Fe-Ni) with a small number of pores. As the HIP temperature increased, the morphology of the coating gradually transforms from a large hard-phase+ bonding-phase to a uniform and small hard phase, and the hardness values of coating are all greater than 1100 HV1. For transition layer, with the temperature of HIP process increased, element diffusion ability was improved and transition layer was disappeared at 1150℃. As the same time, the strength and hardness of the 06Cr13Ni4Mo stainless steel has been reduced with the temperature of HIP pressing improved, while which plasticity and impact energy are improved.