Abstract: A method for determining the compressive strength of diamond micro-powder deposits was studied, the force state of this method was close to that of polycrystalline diamond products, and the diamond micro-powder strength characterized by static pressure crushing was stronger than that characterized by the traditional impact toughness testing method. The diamond mixed powders were used for the compressive strength testing, the compressive strength of the diamond micro-powders was characterized by fragmentation rate, and the diamond mixed powders were assembled into the polycrystalline diamond composite teeth. The mechanical properties of the polycrystalline diamond composite teeth were tested. In the results, the compressive strength of diamond micro-powder deposits is positively correlated with the morphology of diamond micro-powders. For the EZ25~35 μm diamond micro-powders, the compressive strength is 79.30, the sphericity is 0.4119, and the roundness is 0.7176. The compressive strength of the HZ25~35 μm micro-powders is 86.04, the sphericity is 0.6178, and the roundness is 0.8517. The compressive strength of the diamond micro-powder deposits is also related to the content of internal impurities in the diamond micro-powders. For the EZ8~12 μm diamond micro-powders, the compressive strength of the type II micro-powder samples with the total internal impurity content (mass fraction) of 25×10^‒6~40×10^‒6 is 94.73, that of the type IV micro-powder samples with the total internal impurity content (mass fraction) of 10×10^‒6~25×10^‒6 is 98.78, and that of the type VIII micro-powder samples with the total internal impurity content (mass fraction) of 5×10^‒6~10×10^‒6 is 99.07. The compressive strength of the diamond micro-powder deposits is also negatively correlated with the particle size of the diamond micro-powders. Using the revised model to compare the compressive strengths of the diamond micro-powders with two particle sizes, the compressive strength of the micro-powders with the particle size of 4~8 μm is 97.90, that of the micro-powders with the particle size of 15~25 μm is 85.40, and that of the micro-powders with the particle size of 8~16 μm is 82.30. The mechanical properties of the polycrystalline diamond composite teeth are positively correlated with the mixed powders. Since the compressive strength of the diamond micro-powder deposits is closely related to the physical and chemical parameters of diamond micro-powders and the mechanical properties of the polycrystalline diamond composite teeth, the compressive strength detection method can be used as an important parameter for evaluating the performance of diamond micro-powders.