Abstract: The 90.0W‒7.0Ni‒3.0Fe and 90.0W‒6.3Ni‒2.7Fe‒1.0Re alloys were prepared by mechanical alloying and vacuum sintering, and the effects of sintering temperatures on the microstructure and mechanical properties of those two alloys were investigated. The results show that the Re is mainly dissolved into the W particles to form W‒Re solid solution, and part of Re is dissolved into the matrix phase, which refines the grain size by suppressing the dissolution-precipitation process of W particles. With the increase of sintering temperature, the W particles transform from irregular shape to spherical shape, and the matrix phase is gradually homogenized, showing the transformation from solid-phase sintering to liquid-phase sintering. The 90.0W‒6.3Ni‒2.7Fe‒1.0Re alloys are presented the highest tensile strength of 1157.2 MPa at 1460 ℃. The tensile strength reaches 911.4 MPa at 1480 ℃, and the elongation reaches 15.4%, due to the synergistic effect of fine-grain strengthening and solid solution strengthening.