Abstract: Based on the patent data for high-entropy alloy catalysts, the relationship between the patent application trend and technological life cycle, the target country and region, and the major research institution were analyzed in this study. The preparation techniques, application areas, and catalytic performance of high-entropy alloy catalysts were summarized. In the results, both the number of patent applications and applicants show the rapid growth. China is the primary target country for these patents, and Chinese research institutions hold the dominant position in terms of both the number and ranking of patent filings. The main preparation methods of high-entropy alloy catalysts disclosed in patents include the magnetron sputtering, electrospinning, electrochemical deposition, wet chemistry, dealloying, high-energy rapid reaction, and mechanical alloying. The application fields of high-entropy alloy catalysts span the energy conversion and storage, the environmental catalytic treatment, the chemical synthesis and transformation, and the advanced materials development. The research directions of high-entropy alloy catalysts focus on optimizing the catalyst composition, improving the preparation conditions, and expanding the application domains.