Abstract: To solve the problems of difficult particle size control and easy agglomeration for the nano-copper powders prepared by liquid-phase reduction, the normal method (NMM), complex reduction method (CRM), and alcohol solvent reduction method (ARM) were compared, and the effects of reaction temperature, reaction time, and stirring rate on the morphology, particle size, and dispersion of copper powders were systematically investigated. The results show that the alcohol solvent method and complex method are significantly superior to the normal method in regulating particle size distribution and improving dispersion. Especially, the alcohol solvent method, using glycerol as both the solvent and the reducing agent, successfully prepares the spherical nano-copper powders with average particle size of about 200 nm with good dispersion, due to a slow rate of restoration and excellent surface modification capabilities. The optimal process parameters (reaction temperature, reaction time, and stirring rate) were clarified for the three methods, which is 80 ℃, 90 min, and 400 r·min⁻¹ for NMM (the prepared copper powders with particle size of about 300 nm), 90 ℃, 90 min, and 300 r·min⁻¹ for CRM (the prepared copper powders with particle size of about 250 nm), and 160 ℃, 120 min, and 300 r·min⁻¹ for ARM (the prepared copper powders with particle size of about 200 nm).