Abstract: Molybdenum disulfide has been widely used in electronic devices, catalysts, and biomedical fields, due to the special layered structure and the unique properties. The lubrication performance, photoelectric performance, and catalytic degradation properties of molybdenum disulfide were briefly reviewed in this paper, the application and research status of molybdenum disulfide in lithium-ion batteries, supercapacitors, biomedicine, biosensors, and photocatalysis fields were introduced, and the future development trend of molybdenum disulfide is proposed based on the research background and development status.