Abstract: Molybdenum disilicide (MoSi2) coating has excellent high-temperature oxidation resistance which is widely used for the protection of various materials. Combined with the current research status, the advantages of different processes for preparing MoSi2 coatings and the quality differences of prepared MoSi2 coatings are discussed. In this paper, several preparation method MoSi2 are compared, including plasma spraying method, pack cementation method, slurry method, molten salt method, magnetron sputtering method, chemical vapor deposition method, laser cladding method and spark plasma sintering method. The properties of MoSi2 monolayer and composite coatings prepared by different processes are discussed. Finally, the advantages and disadvantages of MoSi2 coatings prepared by different processes are summarized preparing. The improvement of the MoSi2 coating preparation process and the development direction of MoSi2 coating are prospected.